Symposium 7

February 2, 2015
9:00 hrs Inauguration
9:30 hrs Inaugural Address

Nuclear reprogramming and cell replacement prospects.

Sir John Gurdon, DPhil DSc FRS
2012 Nobel Prize in Medicine
Distinguished Group Leader in the Wellcome Trust / CRUK Gurdon Institute, Cambridge, UK

11:00 hrs Exhibition & Poster Session Inauguration
  
Session I
11:45 hrs

Introductory Remarks: Richard DiMarchi, Ph.D.
2014 inductee to the National Inventors Hall of Fame 
Standiford H. Cox Distinguished Professor of Chemistry
                                       Linda & Jack Gill Chair in Biomolecular Sciences
                                       Indiana University

 Chairpersons:
  • T. K. Chakraborty, Ph.D., Professor, Department of Organic Chemistry, Indian Institute of Science,     Bangalore
  • Dhavalkumar D. Patel, M.D., Ph.D., Head, Novartis Institute of Biomedical Research Europe, Basel,      Switzerland
12:00 hrs

Design of drugs to treat influenza A virus infections and tissue fibrosis.

Bill DeGrado, Ph.D.

Professor, The DeGrado Laboratory
Department of Pharmaceutical Chemistry
University of California, San Francisco, USA

12:45 hrs

Adapting Proteostasis to Ameliorate Disease Pharmacologically

Jeff Kelly, Ph.D
Lita Annenberg Hazen Professor of Chemistry
Chairman, Department of Molecular and Experimental Medicine
The Kelly Group, The Scripps Research Insitute
La Jolla, California, USA

13:30 hrs Lunch
14:30 hrs

Cell-penetrating Mini-proteins

Gregory L. Verdine, Ph.D

Erving Professor of Chemistry
Harvard Department of Stem Cell and Regenerative Biology
Harvard University
Cambridge, USA

15:00 hrs

New drug discovery from natural products at CSIR-IIIM Jammu

Ram Vishwakarma, Director
IIIM Jammu and CSIR-Central Drug Research Institute / Council of Scientific & Industrial Research, Lucknow, UP, India

15:30 hrs

Phil

Design, Development and Clinical Evaluation of Ligand-Targeted Therapies and Imaging Agents

Phil Low, Ph.D
Ralph C. Corley Distinguished Professor of Chemistry and Director of the Purdue Center for Drug Discovery—Biochemistry, USA

16:00 hrs Tea Break
16:30 hrs

Butelase 1 for C-terninal-specific Ligation and Macrocyclization of Peptides and Proteins

James P. Tam, Ph.D.
Professor, Division of Structural Biology & Biochemistry
School of Biological Sciences, Nanyang Technological University, Singapore

17:00 hrs

Chemical Biotechnology Applied to Metabolic Diseases

Richard DiMarchi, Ph.D.
Standiford H. Cox Distinguished Professor of Chemistry
Linda & Jack Gill Chair in Biomolecular Sciences
Indiana University

17:45 hrs

Panel Discussion

 

February 3, 2015
Session II

  Chairpersons:
  • Dr. D. Ramaiah, F.A.Sc; Director, CSIR-North East Institute of Science and Technology
    (CSIR-NEIST)
  • Professor Alok Dhawan; Director, Institute of Life Sciences (ILS)

9:00 hrs

Novel approaches to the prevention and treatment of type 2 diabetes

Matthias H. Tschöp, M.D, Ph.D
Alexander-von-Humboldt Professor, Research Director, Helmholtz Diabetes Center
Director, Institute for Diabetes and Obesity, Helmholtz Zentrum München
Chair, Division of Metabolic Diseases, Department of Medicine, Technische Universität München

09:45 hrs Prof Samir Bhattacharya

A small antidiabetic molecule prevents lipid induced insulin resistance through PPARγ dependent and independent pathways

Prof. Samir Bhattacharya, Ph.D, FNA, FASc, FNASc
(Former Director Indian Institute of Chemical Biology, Kolkata)
Emeritus Professor, NASI Senior Scientist,
School of Life Science, Visva-Bharati , Santiniketan

CSIR-North-East Institute of Science and Technology, Jorhat
10:30 hrs

Tea Break & Poster Session

Chairpersons:
  • Dr. D T Mourya, Director, National Institute of Virology, Pune
  • Dr Reinhard Glueck, CSO, Zydus Vaccines
11:30 hrs

Dhavalkumar

TARGETING THE IL-17 PATHWAY IN AUTOIMMUNE DISEASES

Dhavalkumar D. Patel, M.D., Ph.D.
Head, Novartis Institute of Biomedical Research Europe,
Basel, Switzerland

12:15 hrs

Challenges and Opportunities in Development of Innovative Vaccines for the 21st Century

Rahul Singhvi, ScD
COO, Global Vaccine Business Unit
Takeda Pharmaceuticals, Inc. USA

13:00 hrs

Lunch

Session III
Chairpersons:
  • Charles F. Burant, M.D., Ph.D; Dr. Robert C. and Veronica Atkins Professor of Metabolism,
    The Burant Lab, University of Michigan Medical School, USA
  • Bill DeGrado, Ph.D.; Professor, The DeGrado Laboratory, Department of Pharmaceutical
    Chemistry, University of California, San Francisco
14:00 hrs

In search of novel therapeutic approaches to improve insulin sensitivity

Philip Larsen, M.D, Ph.D

Global Head of Diabetes Research and Translational Science,
Sanofi Aventis

14.30 hrs Naga Chalasani

Cardiovascular risk milieu in nonalcoholic fatty liver disease

Naga Chalasani, FACG
Professor of Medicine, Professor of Cellular & Integrative Physiology
Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, USA

15:00 hrs

Saroglitazar: A novel PPAR α /γ agonist for NASH

Dr. Mukul Jain
Senior V P, Pharmacology & Toxicology
Zydus Research Center


15:30 hrs

NASH/NAFLD biomarkers: Are we stuck with biopsies?

Dr. Marcus Hompesch
President, CEO and Founder
Profil Institute for Clinical Research, Inc, USA

16:00 hrs Tea Break
16:30 hrs

Diabetes:  The Greatest Epidemic in the 21st Century?

Paul Zimmet, AO MD PhD FRACP FRCP FTSE

Director Emeritus, Victor Smorgon Diabetes Centre,
Baker IDI Heart and Diabetes Institute
Adjunct Professor, Monash University
Honorary President, International Diabetes Federation
Chair, Programme Committee, World Diabetes Congress 2013
Melbourne, Australia

17:00 hrs Saukat Sadikot

Controlling the Tsunami:In our "Stars" or in our "Hands”

Shaukat M. Sadikot
President-Elect, International Diabetes Federation 2013-2015,
President of DiabetesIndia
Consultant Endocrinology, Jaslok Hospital and Research Center

17:30 hrs

Achieving better research and clinical outcomes in mHealth age

Viren Mehta, Ph.D.
Chairman, Gather Health Limited
Founder, Mehta Partners, LLC.

18:00-18:30 hrs

Panel Discussion

 

February 4, 2015
Session IV

  Chairpersons:
  • Naga Chalasani, MD,FACG; Professor of Medicine, Professor of Cellular & Integrative
    Physiology, Division of Gastroenterology and Hepatology, Indiana University School of Medicine,
    Indianapolis, USA
  • Paul Zimmet, AO MD PhD FRACP FRCP FTSE; Director Emeritus, Victor Smorgon Diabetes
    Centre, Baker IDI Heart and Diabetes Institute, Australia

9:00 hrs

Discovering and Developing Drugs in India : A Scientific and Regulatory Perspective

Dr. Y.K.Gupta, MBBS, MD,FAMS,FNASc,FIPS,FIAN
Professor and Head, Pharmacology, AIIMS, India

 

09:30 hrs

Reprogramming of PPARγ super-enhancers during browning of human adipocytes

Susanne Mandrup, Ph.D.

Professor, Department of Biochemistry and Molecular Biology
University of Southern Denmark

 

10:15 hrs

Parenchymal-stromal Cell Interaction in Metabolic Diseases

Yoshihiro Ogawa, M.D., Ph.D.

Professor and Chairman
Department of Molecular Endocrinology and Metabolism,
Graduate School of Medical and Dental Sciences,
Tokyo Medical and Dental University, Japan

11:15 hrs

Tea Break

11:30 hrs

Ajay Chawla

Innate Mechanisms of Metabolic Homeostasis

Ajay Chawla, M.D., Ph.D.
Professor, Cardiovascular Research Institute,
University of California, San Francisco,

12:15 hrs

Multifaceted function of the transcription regulator PPAR

Walter Wahli, Ph.D
Professor, Center for Integrative Genomics, University of Lausanne, Switzerland, Professor of Metabolic Disease, Lee Kong Chian School of Medicine, Imperial College London & Nanyang Technological University, Singapore General Hospital, Singapore

13:00 hrs

Lunch

Session V
  Chairpersons:
  • Philip Larsen, MD, Ph.D; Global Head of Diabetes Research and Translational Science,
    Sanofi Aventis
  • Richard DiMarchi, Ph.D; Standiford H. Cox Distinguished Professor of Chemistry, Linda & Jack
    Gill Chair in Biomolecular Sciences, Indiana University, USA
14.00 hrs Anil Bhansali

Non-HDL cholesterol in the management of CVD

Anil Bhansali, DM
Head, Department of Endocrinology,
PGIMER, Chandigarh, India

14:45 hrs Shashank Joshi

Clinicians perspective into current and future therapies of type-2 diabetes mellitus

Shashank R. Joshi MBBS, MD, DM, FACP, FRCP, FACE

Consulting Endocrinologist, Lilavati Hospital in Mumbai, India
  Tea Break
16:00 hrs

Rajendra Jani

Developing New Drugs for Cardiometabolic diseases

Rajendra Jani, Ph.D.
Sr. VP, Clinical R & D, Zydus Cadila

16:45 hrs Charles Burant

Metabolism modulation by diet and drugs, insights into mechanisms of action by metabolomics profiling

Charles F. Burant, M.D., Ph.D
Dr. Robert C. and Veronica Atkins Professor of Metabolism, The Burant Lab
University of Michigan Medical School, USA

17:30 hrs Best Poster Awards
18:00 hrs Vote of Thanks

 

 

 

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